Question
Generally speaking, who is prone to chromosomal abnormalities?
Answer
Chromosomal abnormalities encompass a broad range of conditions, including both numerical and structural abnormalities. While chromosomal abnormalities leading to death are relatively rare in the general population, non-lethal abnormalities are more common. For instance, numerical chromosomal abnormalities can lead to developmental disorders in multiple systems, such as Trisomy 21, Trisomy 18, and Turner’s syndrome. On the other hand, structural chromosomal abnormalities like balanced translocations and Robertsonian translocations typically do not cause growth and developmental abnormalities but may increase the risk of infertility, miscarriage, or fetal chromosomal abnormalities. Individuals carrying these abnormalities may not exhibit any obvious symptoms, but their fertility may be affected.