Question
What is a chromosome abnormality? Which chromosome abnormality is the most severe?
Answer
A chromosome abnormality refers to errors in the process of chromosome division that lead to abnormal gene expression and physical growth and development. These errors may arise from the failure of chromosomes to correctly align at the end of cell division or from breaks and reconnections of chromosomes under the influence of internal and external factors. However, some chromosome abnormalities may be polymorphic phenomena or markers of intergenerational inheritance, which may not necessarily lead to infertility, miscarriage, or embryo stagnation.