Question

“Doctor, I am 30 years old, and my husband is 31. I carry a chromosome abnormality, and we plan to undergo third-generation IVF domestically. Will third-generation IVF technology lead to chromosome abnormalities?”

Answer

“Chromosomes are the carriers of genes, and chromosome abnormalities include numerical abnormalities and structural abnormalities. Most fetuses with chromosome abnormalities cannot survive and often result in miscarriage before birth or premature infants and malformed infants after birth. If both partners have issues with chromosome abnormalities, it is recommended to use third-generation IVF technology to screen healthy embryos for implantation, thus avoiding the birth of sick children. However, the selection criteria for embryos in third-generation IVF are very strict, and it is necessary to consult a professional physician to determine if it is suitable for undergoing third-generation IVF.”