Question
I am preparing to have a baby with my husband, but he was diagnosed with a 12th chromosome abnormality during a detailed check-up last week. I’ve heard that this abnormality may be inherited intergenerationally, so I am very worried. Doctor, can chromosomal abnormalities affect pregnancy and childbirth?
Answer
Firstly, it is necessary to understand the specific situation of your husband’s 12th chromosome abnormality, as the impact on fertility varies among different types of chromosomal abnormalities. Some chromosomal abnormalities may lead to infertility, but in some cases, it is possible to naturally conceive and give birth to a healthy baby. However, to reduce the risk of inheritance, consider undergoing third-generation in vitro fertilization techniques (PGD/PGS) to screen embryos, thereby increasing the chance of having a healthy baby. It is recommended that you consult a genetic counselor at a regular hospital to understand detailed genetic information and fertility options. In addition, maintaining good living habits, such as regular sleep patterns and appropriate physical exercise, helps enhance physical condition and immunity.