Question
What Are the Children Born from In Vitro Fertilization with Chromosomal Abnormalities?
Answer
For couples, whether there are abnormalities in the two pairs of chromosomes (such as deletions, translocations, or swaps) indicates a potential risk of genetic defects being passed down to the next generation. Chromosomal abnormalities are also a significant cause of infertility in both men and women. The risk of having children with chromosomal abnormalities is low regardless of whether first-generation, second-generation, or third-generation IVF is used. This is because couples have undergone detailed chromosome checks before embryo transfer, especially with third-generation IVF, which is specifically designed to address chromosomal abnormalities. Before embryo transfer, embryos are comprehensively screened for chromosomal abnormalities, making the likelihood of having children with such abnormalities very low.