Question
If the 21-trisomy screening result is low risk but very close to the critical value, is it necessary to undergo amniocentesis?
Answer
When the risk value of a 21-trisomy screening result is approaching the critical value (1/275), medical professionals may suggest amniocentesis for a more precise diagnosis. This procedure helps confirm the presence of chromosomal abnormalities, such as Down syndrome, and provides a more accurate risk assessment. Although the screening result is low risk, due to the closeness of the risk value to the critical threshold, amniocentesis can provide more detailed information, aiding in the decision to proceed with further diagnosis or monitoring.