What Are the Risks of Conceiving a Child with Chromosomal Abnormalities Through In Vitro Fertilization?

Question

What is the risk of conceiving a child with chromosomal abnormalities through in vitro fertilization?

Answer

For couples, the presence of abnormalities in any of the two pairs of chromosomes (such as deletions, translocations, or inversions) indicates a potential risk of inheriting genetic defects from previous generations. Chromosomal abnormalities are also a significant cause of infertility in both men and women. Regardless of whether they opt for first-generation, second-generation, or third-generation in vitro fertilization, the risk of conceiving a child with chromosomal abnormalities is low. This is because couples undergo thorough chromosome testing before embryo transfer, especially with third-generation in vitro fertilization, which is specifically designed to address chromosomal abnormalities. Before embryo transfer, comprehensive chromosome screening is performed on the embryos, further reducing the risk of chromosomal abnormalities.