Question

What is pediatric neuroblastoma?

Answer

Pediatric neuroblastoma is caused by abnormal proliferation of primitive neural crest cells. It is one of the most common tumors in children. This type of tumor primarily occurs in the sympathetic nervous chain and adrenal medulla, but its location and growth rate can vary greatly, leading to significantly different prognoses. Over the past 30 years, there has been significant progress in the prognosis of pediatric neuroblastoma that is discovered and treated early, but for older and late-stage cases, the prognosis remains pessimistic. Key factors affecting prognosis include age and tumor stage, as well as many other factors that may also influence treatment outcomes and prognosis.