Question
What is the incidence rate of neuroblastoma in children? Recently, a child has shown symptoms of loss of appetite, abdominal swelling, and yellowing of urine, appearing exhausted. After hospital examination, it was diagnosed as neuroblastoma. How common is this disease?
Answer
The incidence rate of neuroblastoma is relatively low, classified as an embryonal tumor that mostly occurs in the hemispheres of the brain. It originates from ancient multipotent sympathetic nerve cells derived from the neural crest, characterized by blue round cell morphology. The disease can lead to symptoms such as high fever, anemia, decreased appetite, abdominal pain, and limb pain, and may cause regional compression symptoms.