Question
The Down syndrome screening result during pregnancy shows a low level of alpha-fetoprotein (AFP). Does this affect the fetus? Is it necessary to have another check or take other measures?
Answer
During pregnancy, alpha-fetoprotein (AFP) is a common screening indicator used to assess the risk of the fetus having certain congenital abnormalities, particularly Down syndrome. A low AFP level is generally considered normal, as it decreases with the progression of pregnancy. However, if the AFP level is significantly below the normal range, doctors may recommend additional tests, such as amniocentesis or cell-free DNA testing, to further evaluate the fetus’s condition. In most cases, a low AFP level does not indicate a problem and requires monitoring based on individual circumstances. It is recommended that pregnant women follow their doctor’s advice and regularly undergo prenatal checks, including ultrasound and fetal heart rate monitoring, to ensure healthy fetal development. Typically, no additional medication treatment is needed, but regular prenatal care and monitoring are very important.