Question
Symptoms of Infant Bile Duct Atresia Jaundice?
Answer
Congenital bile duct atresia is a condition where there is blockage in the intrahepatic and extrahepatic bile ducts, affecting approximately 1 in 8,000 to 14,000 surviving newborns, with significant differences in regions and ethnicities. Cases reported in Asia are more common, with an incidence rate 4-5 times higher in Eastern ethnic groups and a male-to-female ratio of 1:2. This disease may lead to cholestatic liver cirrhosis and is one of the most important digestive surgical diseases in pediatric surgery. It is also the most common indication for pediatric liver transplantation.