Question

How severe is neonatal hemolytic disease?

Answer

Neonatal hemolytic disease can manifest in various clinical symptoms, with the severity depending on the strength of the antigenicity, the individual’s immune response, and the fetal metabolic capacity. In severe cases, it may lead to bilirubin encephalopathy, causing respiratory failure or pulmonary hemorrhage, which could result in death. Some survivors may also have sequelae. Severe cases may require blood transfusion treatment.