Question
Recently, my child has developed many purple-red nodules on their skin, solitary or multiple, round or oval, about the size of soybeans. Some people say this might be neonatal subcutaneous fat necrosis. How can it be differentiated?
Answer
The differentiation of neonatal subcutaneous fat necrosis primarily involves two methods: first, through fungal tissue pathology examination, which is an important diagnostic method for deep fungal infections and can determine whether there is fungal infection in the tissue; second, through tissue pathology examination, observing the condition of the subcutaneous fat tissue. If there is extensive inflammatory cell infiltration, fat necrosis, and the composition of lymphocytes, epithelioid cells, and foreign giant cells, and if there is calcification in the necrotic tissue, then neonatal subcutaneous fat necrosis can be confirmed.