Question
I heard that to determine whether a newborn has hemolytic disease, which is characterized by hemolysis, a special examination is required. So, what are the three tests included in neonatal hemolytic disease detection, and what is the specific examination procedure?
Answer
The preliminary examination for hemolytic anemia includes blood routine and reticulocyte count. In addition, certain hemolytic diseases may require the examination of red blood cell morphology changes (such as spherical, elliptical, mouth-shaped, spiky, target-shaped, fragmentary, and sickle-shaped), red blood cell phagocytosis and autoagglutination phenomena, Heinz bodies, red blood cell osmotic fragility, and red blood cell lifespan for differential diagnosis. Specifically, it is recommended to consult a doctor for more professional guidance.