Question

What are the most common pathogens in neonatal sepsis? I hope to get more valuable advice on this aspect, the more the better, thank you!

Answer

Neonatal sepsis can be divided into early-onset and late-onset types. The early-onset type usually occurs within 7 days after birth, with infections often occurring before or at birth. The main pathogens are Gram-negative bacilli, such as Escherichia coli, and often involve multiple systems. The condition is critical with a high mortality rate. The late-onset type occurs after 7 days following birth, with infections possibly occurring at birth or after birth. Common pathogens include Staphylococcus and Klebsiella pneumoniae, which usually accompany regional infection foci such as umbilical inflammation and pneumonia. The mortality rate is relatively lower. Treatment mainly involves antibiotics targeted at the pathogens, supplemented by symptomatic treatment, and close monitoring of the infant’s vital signs to stabilize them.