Question

A patient came to the clinic with symptoms of dry eyes and dry mouth, but the possibility of dryness syndrome has been ruled out. However, the test results show that the level of immunoglobulin M (IgM) is low, and at the same time, the number of basophils is high. What could be the possible causes of these abnormal indicators, and how should they be handled?

Answer

Low levels of immunoglobulin M (IgM) may be associated with primary agammaglobulinemia, non-IgA and IgG multiple myeloma, Hodgkin’s disease, chronic lymphocytic leukemia, protein-losing gastrointestinal disease, and other conditions. It is recommended to increase protein intake, which can be supplemented through oral or intravenous injection. Treatment should be carried out under medical guidance, and it is suggested that patients maintain good rest and consume nutrient-rich foods. As for the elevated basophil count, the causes may be diverse, and further medical evaluation is needed to determine the specific cause.