Question
The newborn developed fever and hand spasms on the 19th day after birth, accompanied by high jaundice levels. Hospital examination showed that alanine aminotransferase was initially 37, aspartate aminotransferase was 110, and one day later, alanine increased to 237, and total bilirubin, indirect bilirubin, and direct bilirubin were all elevated. How should it be treated? Is it dangerous for newborns to have jaundice accompanied by fever?
Answer
The newborn exhibited fever and spasms on the 19th day after birth, along with elevated jaundice levels. It is necessary to consider whether the spasms are caused by the fever or the high bilirubin levels. Abnormal bilirubin levels accompanied by elevated transaminases suggest possible liver damage. It is recommended to undergo immediate phototherapy to reduce the jaundice and undergo an abdominal ultrasound to rule out the possibility of biliary atresia. If the spasms are caused by high bilirubin levels, they may lead to growth and development complications.