Question

A newborn in the intensive care unit is showing decreased appetite, high jaundice levels, and has been diagnosed with blood infection and ABO hemolytic disease. How should this be treated?

Answer

Neonatal hemolytic disease is caused by a cross-matching immune hemolytic reaction due to incompatibility between the mother’s and the baby’s blood types. Treatment methods include:

  1. Phototherapy: For newborns with early-onset jaundice, timely phototherapy should be administered.
  2. Blood Exchange Treatment: When the progression of jaundice is rapid, and the uncombined bilirubin level in the serum exceeds 342μmol/L, or if this level is not reached but severe neurological abnormalities are present, active blood exchange treatment should be provided.
  3. Blood Transfusion Treatment: If the newborn develops hemolytic anemia, blood transfusion treatment is required. If the newborn has both hemolytic jaundice and sepsis, it can be considered