Question

A patient with chronic hepatitis B and chronic hepatitis B e antigen (HBeAg) positivity was found to have an elevated transaminase level of 98 during a recent routine check-up. How should patients with chronic hepatitis B handle elevated transaminase levels? What are some effective treatment methods?

Answer

An elevated level of transaminase typically indicates mild inflammation in the liver. Alanine aminotransferase (ALT) is widely present in the liver, kidneys, heart, muscles, and other tissues and organs. When these organs, tissues, or cells are active, ALT levels change accordingly. When the body experiences inflammation or injury, ALT is released in large quantities into the bloodstream, leading to a significant increase in its levels. Since ALT activity is highest in liver cells, it is also one of the most sensitive indicators of liver cell damage. For patients with chronic hepatitis B, the first step should be to seek professional medical diagnosis and advice. Treatment methods may include medication, lifestyle adjustments, and regular monitoring of liver function. Medication treatment may involve antiviral drugs and liver-protective drugs to control viral replication and reduce inflammation.