Question
A nine-year-old child has had breast development for half a year and their bone age is equivalent to ten and a half years. Magnetic resonance imaging shows sphenoiditis, ethmoiditis, and bilateral maxillary sinusitis. The pituitary gland shows no abnormalities, and the estradiol level is 62. For children with central precocious puberty who require medication treatment, what possible complications may arise after taking the medication?
Answer
For children with central precocious puberty, the purpose of medication treatment is to suppress gonadal development and delay skeletal maturation in order to increase their height upon adulthood. During the use of such medications, there may be abnormal hormone levels in the body, thyroid function abnormalities, and abnormal secretion of growth hormones. Therefore, regular checks are necessary. If a decrease in growth hormone secretion is detected at the same time, treatment with subcutaneous injection of growth hormone may be required. This medication belongs to a biologic agent and has relatively fewer side effects, but it may cause regional redness, hardening, blisters, or sterile edema at the injection site. The initial injection of the medication may cause vaginal discharge.