Question
What are the main symptoms of Down syndrome, also known as trisomy 21, which is caused by a chromosomal abnormality?
Answer
The main symptoms of Down syndrome include intellectual development delays, distinctive physical features such as facial deformities and frequent tongue protrusion, and developmental delays such as short stature. As individuals grow older, their intellectual development delays become more pronounced, along with delayed physical and sexual development. Additionally, some patients may have congenital heart disease. Currently, there is no effective treatment for Down syndrome.