Question

My good friend’s grandfather is hospitalized due to Down syndrome, and he has been treated for a long time, but he doesn’t understand the disease. I don’t know what the clinical manifestations of Down syndrome are?

Answer

The main clinical manifestations of Down syndrome include: distinctive facial features, wide eye spacing, low nasal bridge, small eye fissures, upward slanting eyes, epicanthic folds on the inner eyelids, low ear placement, sticking out the tongue and drooling, short stature, shorter head circumference, delayed bone age, and short limbs.