Question

The results of the test on June 1, 2005, indicated no chromosomal abnormalities and no treatment had been received. I would like to understand if there is a genetic risk when considering another pregnancy.

Answer

Trisomy 21, also known as Down syndrome, is a common chromosomal disorder. The incidence of this condition in live births ranges approximately from 1 in 600 to 1 in 1000, and the risk of developing the disease increases with the age of the mother. The recurrence risk for standard Trisomy 21 is about 1%, and it increases with advancing maternal age. For translocation cases, the recurrence risk is between 4% and 10%, but if the mother carries a 21q22q translocation, the likelihood of the next generation being affected by the condition is 100%. Prenatal testing for high-risk pregnant women can help with early diagnosis.