Question
The test results show MOM values as follows: AFP 40.5-40.8, HCG below 2.11, freehcg 50.546 ng/ml, PAPP-A above normal range, NT below 2.5mm. The risk of Down syndrome calculated from these values is 1 in 77, the risk of trisomy syndrome is 1 in 35714, the risk of neural tube defects is 0.88, and maternal age risk is 26.21 years old to less than 35 years.
Answer
The Down syndrome screening is conducted by detecting the concentration of fetal protein a and gonadotropin in the mother’s serum, and combining it with the expected delivery date, age, weight, and gestational age at the time of blood collection to calculate the risk factors for Down syndrome fetus. According to the test results you provided, the AFP value is between 40.5 and 40.8, the HCG value is below 2.11, the freehcg value is 50.546 ng/ml, the PAPP-A value is outside the normal range, and the NT value is below 2.5mm. Based on these values, the calculated risk of Down syndrome is 1 in 77, the risk of trisomy syndrome is 1 in 35714, the risk of neural tube defects is 0.88, and the maternal age risk is from 26.21 to less than 35 years old. According to the risk assessment results, you are considered to be in a high-risk group and may have a risk of Down syndrome. To further confirm whether there is a Down syndrome, please undergo amniocentesis and fetal chromosome testing.