Question
My husband and I have incompatible blood types; he is type B and I am type O. Our firstborn son experienced hemolytic disease, which required a total blood transfusion. Now, with our second child, we have checked our blood types and the incidence of hemolytic disease, and the IgG anti-B antibody titer result is 512, which is much higher than the normal range of 0-256, indicating a high possibility of hemolysis. What medications can I take during pregnancy to intervene or reduce the hemolysis level?
Answer
Generally, interventions during pregnancy are not very effective, but you can consult with your local hospital doctor about whether to intervene with immunoglobulins. It is recommended to pay attention to postpartum care, closely monitor the baby’s jaundice situation after birth, and test for reticulocytes and neonatal hemolysis to determine if the baby has hemolysis. Not all hemolytic conditions require a total blood transfusion treatment; it depends on the severity of the baby’s hemolysis. Some hemolytic jaundice can be treated with intravenous immunoglobulin, albumin, and phototherapy. During pregnancy, you can pay attention to rest, maintain a cheerful mood, participate in moderate exercise to strengthen your physique, and maintain regular sleep and diet. Please strictly control your diet and maintain a balanced nutrition.