Question

How should the prenatal test report for newborn hemolytic disease be interpreted? The report shows that the female is B/RH negative, and the male is type B, with the female’s serum neutralizing IgM antibodies reacting with the male’s red blood cells.

Answer

Being B/RH negative means that the female cannot receive RH positive blood because the antigens in RH positive blood can stimulate the production of RH antibodies in RH negative individuals. If she receives RH positive blood again, it may lead to a hemolytic transfusion reaction. Based on your situation, you can bear your first child. In the first pregnancy of an RH negative woman, the amount of antibodies produced is usually not enough to cause fetal disease. However, if the first child is RH positive, future pregnancies may be affected.